Absence of rapid selection for acyclovir or penciclovir resistance following suboptimal oral prodrug therapy of HSV-infected mice

BACKGROUND: Acyclovir (ACV) resistant herpes simplex virus (HSV) isolates can be readily selected in animal infection models receiving suboptimal ACV treatment, however no comparative studies of the emergence of resistance following suboptimal treatment with valacyclovir (VCV) or famciclovir (FCV),...

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Hauptverfasser: Sarisky, Robert T, Bartus, H Ron, Dennis, Shelley A, Quail, Matthew R, Nguyen, Tammy T, Wittrock, Robert J, Halsey, Wendy S, Bacon, Teresa H, Leary, Jeffry J, Sutton, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2001
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC61449/
https://ncbi.nlm.nih.gov/pubmed/11749671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-1-24
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