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Processing of DNA Ends in the Maintenance of Genome Stability
DNA double-strand breaks (DSBs) are particularly hazardous lesions as their inappropriate repair can result in chromosome rearrangements, an important driving force of tumorigenesis. DSBs can be repaired by end joining mechanisms or by homologous recombination (HR). HR requires the action of several...
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| Publicado no: | Front Genet |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6143663/ https://ncbi.nlm.nih.gov/pubmed/30258457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00390 |
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