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Processing of DNA Ends in the Maintenance of Genome Stability

DNA double-strand breaks (DSBs) are particularly hazardous lesions as their inappropriate repair can result in chromosome rearrangements, an important driving force of tumorigenesis. DSBs can be repaired by end joining mechanisms or by homologous recombination (HR). HR requires the action of several...

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Bibliografski detalji
Izdano u:Front Genet
Glavni autori: Bonetti, Diego, Colombo, Chiara Vittoria, Clerici, Michela, Longhese, Maria Pia
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143663/
https://ncbi.nlm.nih.gov/pubmed/30258457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00390
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