CLEC16A regulates splenocyte and NK cell function in part through MEK signaling

CLEC16A is implicated in multiple autoimmune diseases. We generated Clec16a inducible knockout (KO) mice to examine the functional link between CLEC16A auto-inflammation and autoimmunity. Clec16a KO mice exhibited weight loss and thymic and splenic atrophy. Mitochondrial potential was lowered in KO...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Pandey, Rahul, Bakay, Marina, Hain, Heather S., Strenkowski, Bryan, Elsaqa, Barakat Z. B., Roizen, Jeffrey D., Kushner, Jake A., Orange, Jordan S., Hakonarson, Hakon
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2018
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143231/
https://ncbi.nlm.nih.gov/pubmed/30226884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0203952
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia