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Novel antibodies against GPIbα inhibit pulmonary metastasis by affecting vWF-GPIbα interaction
BACKGROUND: Platelet glycoprotein Ibα (GPIbα) extracellular domain, which is part of the receptor complex GPIb-IX-V, plays an important role in tumor metastasis. However, the mechanism through which GPIbα participates in the metastatic process remains unclear. In addition, potential bleeding complic...
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| Izdano u: | J Hematol Oncol |
|---|---|
| Glavni autori: | , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6142402/ https://ncbi.nlm.nih.gov/pubmed/30223883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-018-0659-4 |
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