Novel antibodies against GPIbα inhibit pulmonary metastasis by affecting vWF-GPIbα interaction

BACKGROUND: Platelet glycoprotein Ibα (GPIbα) extracellular domain, which is part of the receptor complex GPIb-IX-V, plays an important role in tumor metastasis. However, the mechanism through which GPIbα participates in the metastatic process remains unclear. In addition, potential bleeding complic...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Hematol Oncol
Main Authors: Qi, Yingxue, Chen, Wenchun, Liang, Xinyu, Xu, Ke, Gu, Xiangyu, Wu, Fengying, Fan, Xuemei, Ren, Shengxiang, Liu, Junling, Zhang, Jun, Li, Renhao, Liu, Jianwen, Liang, Xin
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142402/
https://ncbi.nlm.nih.gov/pubmed/30223883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-018-0659-4
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