mRNA-binding protein tristetraprolin is essential for cardiac response to iron deficiency by regulating mitochondrial function

Cells respond to iron deficiency by activating iron-regulatory proteins to increase cellular iron uptake and availability. However, it is not clear how cells adapt to conditions when cellular iron uptake does not fully match iron demand. Here, we show that the mRNA-binding protein tristetraprolin (T...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Sato, Tatsuya, Chang, Hsiang-Chun, Bayeva, Marina, Shapiro, Jason S., Ramos-Alonso, Lucia, Kouzu, Hidemichi, Jiang, Xinghang, Liu, Ting, Yar, Sumeyye, Sawicki, Konrad T., Chen, Chunlei, Martínez-Pastor, María Teresa, Stumpo, Deborah J., Schumacker, Paul T., Blackshear, Perry J., Ben-Sahra, Issam, Puig, Sergi, Ardehali, Hossein
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2018
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142244/
https://ncbi.nlm.nih.gov/pubmed/29915044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804701115
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