mRNA-binding protein tristetraprolin is essential for cardiac response to iron deficiency by regulating mitochondrial function

Cells respond to iron deficiency by activating iron-regulatory proteins to increase cellular iron uptake and availability. However, it is not clear how cells adapt to conditions when cellular iron uptake does not fully match iron demand. Here, we show that the mRNA-binding protein tristetraprolin (T...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Sato, Tatsuya, Chang, Hsiang-Chun, Bayeva, Marina, Shapiro, Jason S., Ramos-Alonso, Lucia, Kouzu, Hidemichi, Jiang, Xinghang, Liu, Ting, Yar, Sumeyye, Sawicki, Konrad T., Chen, Chunlei, Martínez-Pastor, María Teresa, Stumpo, Deborah J., Schumacker, Paul T., Blackshear, Perry J., Ben-Sahra, Issam, Puig, Sergi, Ardehali, Hossein
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2018
Предметы:
PNAS Plus
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142244/
https://ncbi.nlm.nih.gov/pubmed/29915044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804701115
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