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mTOR Regulates Cellular Iron Homeostasis through Tristetraprolin

Iron is an essential cofactor with unique redox properties. Iron regulatory proteins 1 and 2 (IRP1/2) have been established as important regulators of cellular iron homeostasis, but little is known about the role of other pathways in this process. Here we report that the mammalian target of rapamyci...

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Detalhes bibliográficos
Main Authors: Bayeva, Marina, Khechaduri, Arineh, Puig, Sergi, Chang, Hsiang-Chun, Patial, Sonika, Blackshear, Perry J., Ardehali, Hossein
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594686/
https://ncbi.nlm.nih.gov/pubmed/23102618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2012.10.001
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