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mTOR Regulates Cellular Iron Homeostasis through Tristetraprolin

Iron is an essential cofactor with unique redox properties. Iron regulatory proteins 1 and 2 (IRP1/2) have been established as important regulators of cellular iron homeostasis, but little is known about the role of other pathways in this process. Here we report that the mammalian target of rapamyci...

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Hlavní autoři: Bayeva, Marina, Khechaduri, Arineh, Puig, Sergi, Chang, Hsiang-Chun, Patial, Sonika, Blackshear, Perry J., Ardehali, Hossein
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594686/
https://ncbi.nlm.nih.gov/pubmed/23102618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2012.10.001
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