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mTOR Regulates Cellular Iron Homeostasis through Tristetraprolin

Iron is an essential cofactor with unique redox properties. Iron regulatory proteins 1 and 2 (IRP1/2) have been established as important regulators of cellular iron homeostasis, but little is known about the role of other pathways in this process. Here we report that the mammalian target of rapamyci...

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Main Authors: Bayeva, Marina, Khechaduri, Arineh, Puig, Sergi, Chang, Hsiang-Chun, Patial, Sonika, Blackshear, Perry J., Ardehali, Hossein
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594686/
https://ncbi.nlm.nih.gov/pubmed/23102618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2012.10.001
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