Novel Clade C-I Clostridium difficile strains escape diagnostic tests, differ in pathogenicity potential and carry toxins on extrachromosomal elements

The population structure of Clostridium difficile currently comprises eight major genomic clades. For the highly divergent C-I clade, only two toxigenic strains have been reported, which lack the tcdA and tcdC genes and carry a complete locus for the binary toxin (CDT) next to an atypical TcdB monot...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Ramírez-Vargas, Gabriel, López-Ureña, Diana, Badilla, Adriana, Orozco-Aguilar, Josué, Murillo, Tatiana, Rojas, Priscilla, Riedel, Thomas, Overmann, Jörg, González, Gabriel, Chaves-Olarte, Esteban, Quesada-Gómez, Carlos, Rodríguez, César
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6141592/
https://ncbi.nlm.nih.gov/pubmed/30224751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32390-6
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