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Novel Clade C-I Clostridium difficile strains escape diagnostic tests, differ in pathogenicity potential and carry toxins on extrachromosomal elements

The population structure of Clostridium difficile currently comprises eight major genomic clades. For the highly divergent C-I clade, only two toxigenic strains have been reported, which lack the tcdA and tcdC genes and carry a complete locus for the binary toxin (CDT) next to an atypical TcdB monot...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ramírez-Vargas, Gabriel, López-Ureña, Diana, Badilla, Adriana, Orozco-Aguilar, Josué, Murillo, Tatiana, Rojas, Priscilla, Riedel, Thomas, Overmann, Jörg, González, Gabriel, Chaves-Olarte, Esteban, Quesada-Gómez, Carlos, Rodríguez, César
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6141592/
https://ncbi.nlm.nih.gov/pubmed/30224751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32390-6
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