Novel Clade C-I Clostridium difficile strains escape diagnostic tests, differ in pathogenicity potential and carry toxins on extrachromosomal elements

The population structure of Clostridium difficile currently comprises eight major genomic clades. For the highly divergent C-I clade, only two toxigenic strains have been reported, which lack the tcdA and tcdC genes and carry a complete locus for the binary toxin (CDT) next to an atypical TcdB monot...

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Udgivet i:Sci Rep
Main Authors: Ramírez-Vargas, Gabriel, López-Ureña, Diana, Badilla, Adriana, Orozco-Aguilar, Josué, Murillo, Tatiana, Rojas, Priscilla, Riedel, Thomas, Overmann, Jörg, González, Gabriel, Chaves-Olarte, Esteban, Quesada-Gómez, Carlos, Rodríguez, César
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6141592/
https://ncbi.nlm.nih.gov/pubmed/30224751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32390-6
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