In vivo animal models confirm an increased virulence potential and pathogenicity of the NAP1/RT027/ST01 genotype within the Clostridium difficile MLST Clade 2

BACKGROUND: Based on MLST analyses the global population of C. difficile is distributed in eight clades, of which Clade 2 includes the “hypervirulent” NAP1/RT027/ST01 strain along with various unexplored sequence types (STs). METHODS: To clarify whether this clinically relevant phenotype is a widesp...

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Detalhes bibliográficos
Publicado no:Gut Pathog
Principais autores: Orozco-Aguilar, Josué, Alfaro-Alarcón, Alejandro, Acuña-Amador, Luis, Chaves-Olarte, Esteban, Rodríguez, César, Quesada-Gómez, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7510272/
https://ncbi.nlm.nih.gov/pubmed/32983262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13099-020-00383-4
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