IL-6 and CXCL8 mediate osteosarcoma-lung interactions critical to metastasis

Osteosarcoma (OS), a malignant tumor of bone, kills through aggressive metastatic spread almost exclusively to the lung. Mechanisms driving this tropism for lung tissue remain unknown, though likely invoke specific interactions between tumor cells and other cells within the lung metastatic niche. Ab...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JCI Insight
Egile Nagusiak: Gross, Amy C., Cam, Hakan, Phelps, Doris A., Saraf, Amanda J., Bid, Hemant K., Cam, Maren, London, Cheryl A., Winget, Sarah A., Arnold, Michael A., Brandolini, Laura, Mo, Xiaokui, Hinckley, John M., Houghton, Peter J., Roberts, Ryan D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2018
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6141177/
https://ncbi.nlm.nih.gov/pubmed/30135299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99791
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