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IL-6 and CXCL8 mediate osteosarcoma-lung interactions critical to metastasis
Osteosarcoma (OS), a malignant tumor of bone, kills through aggressive metastatic spread almost exclusively to the lung. Mechanisms driving this tropism for lung tissue remain unknown, though likely invoke specific interactions between tumor cells and other cells within the lung metastatic niche. Ab...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6141177/ https://ncbi.nlm.nih.gov/pubmed/30135299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99791 |
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