Ursodeoxycholic acid protects against intestinal barrier breakdown by promoting enterocyte migration via EGFR- and COX-2-dependent mechanisms

The intestinal barrier is often disrupted in disease states, and intestinal barrier failure leads to sepsis. Ursodeoxycholic acid (UDCA) is a bile acid that may protect the intestinal barrier. We hypothesized that UDCA would protect the intestinal epithelium in injury models. To test this hypothesis...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Am J Physiol Gastrointest Liver Physiol
Hauptverfasser: Golden, Jamie M., Escobar, Oswaldo H., Nguyen, Michelle V. L., Mallicote, Michael U., Kavarian, Patil, Frey, Mark R., Gayer, Christopher P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139640/
https://ncbi.nlm.nih.gov/pubmed/29672156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00354.2017
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge