Transactivation of EGFR by LPS Induces COX-2 Expression in Enterocytes

Necrotizing enterocolitis (NEC) is the leading cause of gastrointestinal morbidity and mortality in preterm infants. NEC is characterized by an exaggerated inflammatory response to bacterial flora leading to bowel necrosis. Bacterial lipopolysaccharide (LPS) mediates inflammation through TLR4 activa...

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Detalhes bibliográficos
Main Authors: McElroy, Steven J., Hobbs, Stuart, Kallen, Michael, Tejera, Noemi, Rosen, Michael J., Grishin, Anatoly, Matta, Poojitha, Schneider, Claus, Upperman, Jeffrey, Ford, Henri, Polk, D. Brent, Weitkamp, Jörn-Hendrik
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364993/
https://ncbi.nlm.nih.gov/pubmed/22675459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038373
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