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Transactivation of EGFR by LPS Induces COX-2 Expression in Enterocytes

Necrotizing enterocolitis (NEC) is the leading cause of gastrointestinal morbidity and mortality in preterm infants. NEC is characterized by an exaggerated inflammatory response to bacterial flora leading to bowel necrosis. Bacterial lipopolysaccharide (LPS) mediates inflammation through TLR4 activa...

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Détails bibliographiques
Auteurs principaux: McElroy, Steven J., Hobbs, Stuart, Kallen, Michael, Tejera, Noemi, Rosen, Michael J., Grishin, Anatoly, Matta, Poojitha, Schneider, Claus, Upperman, Jeffrey, Ford, Henri, Polk, D. Brent, Weitkamp, Jörn-Hendrik
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364993/
https://ncbi.nlm.nih.gov/pubmed/22675459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038373
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