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EP2 receptor blockade attenuates COX-2 upregulation during intestinal inflammation
High levels of PGE(2) have been implicated in the pathogenesis of intestinal inflammatory disorders such as necrotizing enterocolitis (NEC) and peritonitis. However, PGE(2) has a paradoxical effect: its low levels promote intestinal homeostasis, whereas high levels may contribute to pathology. These...
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| Publicado no: | Shock |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7051888/ https://ncbi.nlm.nih.gov/pubmed/31490357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000001444 |
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