Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation

X-chromosome inactivation (XCI), i.e., the inactivation of one of the female X chromosomes, restores equal expression of X-chromosomal genes between females and males. However, ~10% of genes show variable degrees of escape from XCI between females, although little is known about the causes of variab...

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Luijk, René, Wu, Haoyu, Ward-Caviness, Cavin K, Hannon, Eilis, Carnero-Montoro, Elena, Min, Josine L., Mandaviya, Pooja, Müller-Nurasyid, Martina, Mei, Hailiang, van der Maarel, Silvere M., Relton, Caroline, Mill, Jonathan, Waldenberger, Melanie, Bell, Jordana T., Jansen, Rick, Zhernakova, Alexandra, Franke, Lude, ‘t Hoen, Peter A. C., Boomsma, Dorret I., van Duijn, Cornelia M., van Greevenbroek, Marleen M. J., Veldink, Jan H., Wijmenga, Cisca, van Meurs, Joyce, Daxinger, Lucia, Slagboom, P. Eline, van Zwet, Erik W., Heijmans, Bastiaan T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138682/
https://ncbi.nlm.nih.gov/pubmed/30218040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05714-3
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