Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation

X-chromosome inactivation (XCI), i.e., the inactivation of one of the female X chromosomes, restores equal expression of X-chromosomal genes between females and males. However, ~10% of genes show variable degrees of escape from XCI between females, although little is known about the causes of variab...

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書誌詳細
出版年:Nat Commun
主要な著者: Luijk, René, Wu, Haoyu, Ward-Caviness, Cavin K, Hannon, Eilis, Carnero-Montoro, Elena, Min, Josine L., Mandaviya, Pooja, Müller-Nurasyid, Martina, Mei, Hailiang, van der Maarel, Silvere M., Relton, Caroline, Mill, Jonathan, Waldenberger, Melanie, Bell, Jordana T., Jansen, Rick, Zhernakova, Alexandra, Franke, Lude, ‘t Hoen, Peter A. C., Boomsma, Dorret I., van Duijn, Cornelia M., van Greevenbroek, Marleen M. J., Veldink, Jan H., Wijmenga, Cisca, van Meurs, Joyce, Daxinger, Lucia, Slagboom, P. Eline, van Zwet, Erik W., Heijmans, Bastiaan T.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2018
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138682/
https://ncbi.nlm.nih.gov/pubmed/30218040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05714-3
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