Lipin-1 regulation of phospholipid synthesis maintains endoplasmic reticulum homeostasis and is critical for triple-negative breast cancer cell survival

Cancer cells reprogram their metabolism to increase the synthesis of macromolecules for rapid proliferation. Compared to fatty acids, much less is known about the synthesis of phospholipids, which is essential for membrane biogenesis in cancer cells. We found that LPIN1, which encodes lipin-1, a pho...

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Detaylı Bibliyografya
Yayımlandı:FASEB J
Asıl Yazarlar: He, Jingquan, Zhang, Feng, Tay, Li Wei Rachel, Boroda, Salome, Nian, Weiqi, Levental, Kandice R., Levental, Ilya, Harris, Thurl E., Chang, Jeffrey T., Du, Guangwei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Federation of American Societies for Experimental Biology 2017
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137500/
https://ncbi.nlm.nih.gov/pubmed/28347999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201601353R
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