Endoplasmic reticulum maintains ion homeostasis required for plasma membrane repair

Of the many crucial functions of the ER, homeostasis of physiological calcium increase is critical for signaling. Plasma membrane (PM) injury causes a pathological calcium influx. Here, we show that the ER helps clear this surge in cytoplasmic calcium through an ER-resident calcium pump, SERCA, and...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Cell Biol
Main Authors: Chandra, Goutam, Sreetama, Sen Chandra, Mázala, Davi A.G., Charton, Karine, VanderMeulen, Jack H., Richard, Isabelle, Jaiswal, Jyoti K.
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2021
Teme:
Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7953257/
https://ncbi.nlm.nih.gov/pubmed/33688936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202006035
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