Endoplasmic reticulum maintains ion homeostasis required for plasma membrane repair

Of the many crucial functions of the ER, homeostasis of physiological calcium increase is critical for signaling. Plasma membrane (PM) injury causes a pathological calcium influx. Here, we show that the ER helps clear this surge in cytoplasmic calcium through an ER-resident calcium pump, SERCA, and...

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Bibliografiset tiedot
Julkaisussa:J Cell Biol
Päätekijät: Chandra, Goutam, Sreetama, Sen Chandra, Mázala, Davi A.G., Charton, Karine, VanderMeulen, Jack H., Richard, Isabelle, Jaiswal, Jyoti K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Rockefeller University Press 2021
Aiheet:
Report
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7953257/
https://ncbi.nlm.nih.gov/pubmed/33688936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202006035
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