Mdm1 maintains endoplasmic reticulum homeostasis by spatially regulating lipid droplet biogenesis

Lipid droplets (LDs) serve as cytoplasmic reservoirs for energy-rich fatty acids (FAs) stored in the form of triacylglycerides (TAGs). During nutrient stress, yeast LDs cluster adjacent to the vacuole/lysosome, but how this LD accumulation is coordinated remains poorly understood. The ER protein Mdm...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Hariri, Hanaa, Speer, Natalie, Bowerman, Jade, Rogers, Sean, Fu, Gang, Reetz, Evan, Datta, Sanchari, Feathers, J. Ryan, Ugrankar, Rupali, Nicastro, Daniela, Henne, W. Mike
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446837/
https://ncbi.nlm.nih.gov/pubmed/30808705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201808119
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