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Cerebellar ataxia disease–associated Snx14 promotes lipid droplet growth at ER–droplet contacts

Lipid droplets (LDs) are nutrient reservoirs used by cells to maintain homeostasis. Nascent droplets form on the endoplasmic reticulum (ER) and grow following an influx of exogenous fatty acids (FAs). The budding of LDs requires extensive ER–LD crosstalk, but how this is regulated remains poorly und...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Datta, Sanchari, Liu, Yang, Hariri, Hanaa, Bowerman, Jade, Henne, W. Mike
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446855/
https://ncbi.nlm.nih.gov/pubmed/30765438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201808133
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