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Cerebellar ataxia disease–associated Snx14 promotes lipid droplet growth at ER–droplet contacts

Lipid droplets (LDs) are nutrient reservoirs used by cells to maintain homeostasis. Nascent droplets form on the endoplasmic reticulum (ER) and grow following an influx of exogenous fatty acids (FAs). The budding of LDs requires extensive ER–LD crosstalk, but how this is regulated remains poorly und...

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Bibliografski detalji
Izdano u:J Cell Biol
Glavni autori: Datta, Sanchari, Liu, Yang, Hariri, Hanaa, Bowerman, Jade, Henne, W. Mike
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2019
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446855/
https://ncbi.nlm.nih.gov/pubmed/30765438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201808133
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