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Cerebellar ataxia disease–associated Snx14 promotes lipid droplet growth at ER–droplet contacts
Lipid droplets (LDs) are nutrient reservoirs used by cells to maintain homeostasis. Nascent droplets form on the endoplasmic reticulum (ER) and grow following an influx of exogenous fatty acids (FAs). The budding of LDs requires extensive ER–LD crosstalk, but how this is regulated remains poorly und...
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| 發表在: | J Cell Biol |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Rockefeller University Press
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6446855/ https://ncbi.nlm.nih.gov/pubmed/30765438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201808133 |
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