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Insufficient autophagy: a novel autophagic flux scenario uncovered by impaired liver TFEB-mediated lysosomal biogenesis from chronic alcohol-drinking mice

Macroautophagy/autophagy is a dynamic process, and newly synthesized autophagosomes need to fuse with lysosomes to complete the full process, which is referred to as autophagic degradation or autophagic flux. Therefore, the proper number and function of lysosomes are critical for accomplishing autop...

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Publicat a:Autophagy
Autors principals: Chao, Xiaojuan, Ni, Hong-Min, Ding, Wen-Xing
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135568/
https://ncbi.nlm.nih.gov/pubmed/29969942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1489170
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