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Autophagy-independent function of lipidated LC3 essential for TFEB activation during the lysosomal damage responses

Lysosomes are digestive organelles in cells containing many hydrolases, and also serve as a signaling hub to integrate intracellular and extracellular inputs; therefore, the integrity of lysosomes is critical for cellular homeostasis. Many agents and conditions can damage lysosomal membranes, which...

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Detalles Bibliográficos
Publicado en:Autophagy
Main Authors: Nakamura, Shuhei, Akayama, Shiori, Yoshimori, Tamotsu
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007146/
https://ncbi.nlm.nih.gov/pubmed/33150842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1846292
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