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Dysfunctional lysosomal autophagy leads to peroxisomal oxidative burnout and damage during endotoxin-induced stress

Mammalian peroxisomes are ubiquitous organelles that possess a comprehensive ensemble of more than 50 enzymes. Cells regulate the number of organelles through dynamic interplay between biogenesis and degradation. Under basal conditions, approximately 30% of the peroxisomal pool is turned over daily....

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Bibliographic Details
Main Authors: Vasko, Radovan, Goligorsky, Michael S.
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590273/
https://ncbi.nlm.nih.gov/pubmed/23328407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.23344
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