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Oxidative stress impairs autophagy through oxidation of ATG3 and ATG7
Dysfunctional macroautophagy/autophagy has been causatively linked to aging and the pathogenesis of many diseases, which are also broadly characterized by dysregulated cellular redox. As the autophagy-related (ATG) conjugation systems that mediate autophagosome maturation are cysteine dependent, the...
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| Publicado no: | Autophagy |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6103406/ https://ncbi.nlm.nih.gov/pubmed/29746182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1444311 |
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