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Allosteric regulation through a switch element in the autophagy E2, Atg3
Lipidation of Atg8-family ubiquitin-like proteins (UBLs) plays important roles in macroautophagy/autophagy. This process is catalyzed by an E1-E2-E3 trienzyme cascade, in which an E1 enzyme, Atg7, directs Atg8 to its E2 enzyme, Atg3, forming a thioester bond-linked Atg3~ Atg8 intermediate; then the...
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| Publicado no: | Autophagy |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6984587/ https://ncbi.nlm.nih.gov/pubmed/31690182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1688550 |
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