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Insufficient autophagy: a novel autophagic flux scenario uncovered by impaired liver TFEB-mediated lysosomal biogenesis from chronic alcohol-drinking mice

Macroautophagy/autophagy is a dynamic process, and newly synthesized autophagosomes need to fuse with lysosomes to complete the full process, which is referred to as autophagic degradation or autophagic flux. Therefore, the proper number and function of lysosomes are critical for accomplishing autop...

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Detalles Bibliográficos
Publicado en:Autophagy
Autores principales: Chao, Xiaojuan, Ni, Hong-Min, Ding, Wen-Xing
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135568/
https://ncbi.nlm.nih.gov/pubmed/29969942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1489170
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