Targeting a phospho-STAT3-miRNAs pathway improves vesicular hepatic steatosis in an in vitro and in vivo model

Non-alcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease. Although genetic predisposition and epigenetic factors contribute to the development of NAFLD, our understanding of the molecular mechanism involved in the pathogenesis of the disease is still emerging. Here we in...

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Vydáno v:Sci Rep
Hlavní autoři: Belloni, Laura, Di Cocco, Silvia, Guerrieri, Francesca, Nunn, Abigail D. G., Piconese, Silvia, Salerno, Debora, Testoni, Barbara, Pulito, Claudio, Mori, Federica, Pallocca, Matteo, Sacconi, Andrea, Vivoli, Elisa, Marra, Fabio, Strano, Sabrina, Blandino, Giovanni, Levrero, Massimo, Pediconi, Natalia
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134080/
https://ncbi.nlm.nih.gov/pubmed/30206377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31835-2
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