IL6 Inhibits HBV Transcription by Targeting the Epigenetic Control of the Nuclear cccDNA Minichromosome

The HBV covalently closed circular DNA (cccDNA) is organized as a mini-chromosome in the nuclei of infected hepatocytes by histone and non-histone proteins. Transcription from the cccDNA of the RNA replicative intermediate termed pre-genome (pgRNA), is the critical step for genome amplification and...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Palumbo, Gianna Aurora, Scisciani, Cecilia, Pediconi, Natalia, Lupacchini, Leonardo, Alfalate, Dulce, Guerrieri, Francesca, Calvo, Ludovica, Salerno, Debora, Di Cocco, Silvia, Levrero, Massimo, Belloni, Laura
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651563/
https://ncbi.nlm.nih.gov/pubmed/26580974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142599
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items