Targeting a phospho-STAT3-miRNAs pathway improves vesicular hepatic steatosis in an in vitro and in vivo model

Non-alcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease. Although genetic predisposition and epigenetic factors contribute to the development of NAFLD, our understanding of the molecular mechanism involved in the pathogenesis of the disease is still emerging. Here we in...

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Publicado no:Sci Rep
Main Authors: Belloni, Laura, Di Cocco, Silvia, Guerrieri, Francesca, Nunn, Abigail D. G., Piconese, Silvia, Salerno, Debora, Testoni, Barbara, Pulito, Claudio, Mori, Federica, Pallocca, Matteo, Sacconi, Andrea, Vivoli, Elisa, Marra, Fabio, Strano, Sabrina, Blandino, Giovanni, Levrero, Massimo, Pediconi, Natalia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134080/
https://ncbi.nlm.nih.gov/pubmed/30206377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31835-2
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