Targeting a phospho-STAT3-miRNAs pathway improves vesicular hepatic steatosis in an in vitro and in vivo model

Non-alcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease. Although genetic predisposition and epigenetic factors contribute to the development of NAFLD, our understanding of the molecular mechanism involved in the pathogenesis of the disease is still emerging. Here we in...

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Udgivet i:Sci Rep
Main Authors: Belloni, Laura, Di Cocco, Silvia, Guerrieri, Francesca, Nunn, Abigail D. G., Piconese, Silvia, Salerno, Debora, Testoni, Barbara, Pulito, Claudio, Mori, Federica, Pallocca, Matteo, Sacconi, Andrea, Vivoli, Elisa, Marra, Fabio, Strano, Sabrina, Blandino, Giovanni, Levrero, Massimo, Pediconi, Natalia
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134080/
https://ncbi.nlm.nih.gov/pubmed/30206377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31835-2
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