EZH2, JMJD3, and UTX epigenetically regulate hepatic plasticity inducing retro-differentiation and proliferation of liver cells

Modification of histones by lysine methylation plays a role in many biological processes, and it is dynamically regulated by several histone methyltransferases and demethylases. The polycomb repressive complex contains the H3K27 methyltransferase EZH2 and controls dimethylation and trimethylation of...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Pediconi, Natalia, Salerno, Debora, Lupacchini, Leonardo, Angrisani, Annapaola, Peruzzi, Giovanna, De Smaele, Enrico, Levrero, Massimo, Belloni, Laura
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614397/
https://ncbi.nlm.nih.gov/pubmed/31285428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1755-2
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