EZH2, JMJD3, and UTX epigenetically regulate hepatic plasticity inducing retro-differentiation and proliferation of liver cells

Modification of histones by lysine methylation plays a role in many biological processes, and it is dynamically regulated by several histone methyltransferases and demethylases. The polycomb repressive complex contains the H3K27 methyltransferase EZH2 and controls dimethylation and trimethylation of...

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Pubblicato in:Cell Death Dis
Autori principali: Pediconi, Natalia, Salerno, Debora, Lupacchini, Leonardo, Angrisani, Annapaola, Peruzzi, Giovanna, De Smaele, Enrico, Levrero, Massimo, Belloni, Laura
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614397/
https://ncbi.nlm.nih.gov/pubmed/31285428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1755-2
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