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EZH2, JMJD3, and UTX epigenetically regulate hepatic plasticity inducing retro-differentiation and proliferation of liver cells

Modification of histones by lysine methylation plays a role in many biological processes, and it is dynamically regulated by several histone methyltransferases and demethylases. The polycomb repressive complex contains the H3K27 methyltransferase EZH2 and controls dimethylation and trimethylation of...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Pediconi, Natalia, Salerno, Debora, Lupacchini, Leonardo, Angrisani, Annapaola, Peruzzi, Giovanna, De Smaele, Enrico, Levrero, Massimo, Belloni, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614397/
https://ncbi.nlm.nih.gov/pubmed/31285428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1755-2
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