Localization of RNAi Machinery to Axonal Branch Points and Growth Cones Is Facilitated by Mitochondria and Is Disrupted in ALS

Local protein synthesis in neuronal axons plays an important role in essential spatiotemporal signaling processes; however, the molecular basis for the post-transcriptional regulation controlling this process in axons is still not fully understood. Here we studied the axonal mechanisms underlying th...

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Foilsithe in:Front Mol Neurosci
Main Authors: Gershoni-Emek, Noga, Altman, Topaz, Ionescu, Ariel, Costa, Christopher J., Gradus-Pery, Tal, Willis, Dianna E., Perlson, Eran
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2018
Ábhair:
Molecular Neuroscience
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134038/
https://ncbi.nlm.nih.gov/pubmed/30233312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00311
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