miR126-5p Downregulation Facilitates Axon Degeneration and NMJ Disruption via a Non–Cell-Autonomous Mechanism in ALS

Axon degeneration and disruption of neuromuscular junctions (NMJs) are key events in amyotrophic lateral sclerosis (ALS) pathology. Although the disease's etiology is not fully understood, it is thought to involve a non–cell-autonomous mechanism and alterations in RNA metabolism. Here, we ident...

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Publicado en:J Neurosci
Autores principales: Maimon, Roy, Ionescu, Ariel, Bonnie, Avichai, Sweetat, Sahar, Wald-Altman, Shane, Inbar, Shani, Gradus, Tal, Trotti, Davide, Weil, Miguel, Behar, Oded, Perlson, Eran
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2018
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001038/
https://ncbi.nlm.nih.gov/pubmed/29773756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3037-17.2018
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