miR126-5p Downregulation Facilitates Axon Degeneration and NMJ Disruption via a Non–Cell-Autonomous Mechanism in ALS

Axon degeneration and disruption of neuromuscular junctions (NMJs) are key events in amyotrophic lateral sclerosis (ALS) pathology. Although the disease's etiology is not fully understood, it is thought to involve a non–cell-autonomous mechanism and alterations in RNA metabolism. Here, we ident...

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Pubblicato in:J Neurosci
Autori principali: Maimon, Roy, Ionescu, Ariel, Bonnie, Avichai, Sweetat, Sahar, Wald-Altman, Shane, Inbar, Shani, Gradus, Tal, Trotti, Davide, Weil, Miguel, Behar, Oded, Perlson, Eran
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2018
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001038/
https://ncbi.nlm.nih.gov/pubmed/29773756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3037-17.2018
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