miR126-5p Downregulation Facilitates Axon Degeneration and NMJ Disruption via a Non–Cell-Autonomous Mechanism in ALS

Axon degeneration and disruption of neuromuscular junctions (NMJs) are key events in amyotrophic lateral sclerosis (ALS) pathology. Although the disease's etiology is not fully understood, it is thought to involve a non–cell-autonomous mechanism and alterations in RNA metabolism. Here, we ident...

詳細記述

保存先:
書誌詳細
出版年:J Neurosci
主要な著者: Maimon, Roy, Ionescu, Ariel, Bonnie, Avichai, Sweetat, Sahar, Wald-Altman, Shane, Inbar, Shani, Gradus, Tal, Trotti, Davide, Weil, Miguel, Behar, Oded, Perlson, Eran
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2018
主題:
Research Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001038/
https://ncbi.nlm.nih.gov/pubmed/29773756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3037-17.2018
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