miR126-5p Downregulation Facilitates Axon Degeneration and NMJ Disruption via a Non–Cell-Autonomous Mechanism in ALS

Axon degeneration and disruption of neuromuscular junctions (NMJs) are key events in amyotrophic lateral sclerosis (ALS) pathology. Although the disease's etiology is not fully understood, it is thought to involve a non–cell-autonomous mechanism and alterations in RNA metabolism. Here, we ident...

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Detaylı Bibliyografya
Yayımlandı:J Neurosci
Asıl Yazarlar: Maimon, Roy, Ionescu, Ariel, Bonnie, Avichai, Sweetat, Sahar, Wald-Altman, Shane, Inbar, Shani, Gradus, Tal, Trotti, Davide, Weil, Miguel, Behar, Oded, Perlson, Eran
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2018
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001038/
https://ncbi.nlm.nih.gov/pubmed/29773756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3037-17.2018
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