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Proteomic Analysis of Dynein-Interacting Proteins in Amyotrophic Lateral Sclerosis Synaptosomes Reveals Alterations in the RNA-Binding Protein Staufen1

Synapse disruption takes place in many neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). However, the mechanistic understanding of this process is still limited. We set out to study a possible role for dynein in synapse integrity. Cytoplasmic dynein is a multisubunit intrace...

詳細記述

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書誌詳細
出版年:Mol Cell Proteomics
主要な著者: Gershoni-Emek, Noga, Mazza, Arnon, Chein, Michael, Gradus-Pery, Tal, Xiang, Xin, Li, Ka Wan, Sharan, Roded, Perlson, Eran
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Biochemistry and Molecular Biology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739670/
https://ncbi.nlm.nih.gov/pubmed/26598648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.049965
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