Proteomic Analysis of Dynein-Interacting Proteins in Amyotrophic Lateral Sclerosis Synaptosomes Reveals Alterations in the RNA-Binding Protein Staufen1

Synapse disruption takes place in many neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). However, the mechanistic understanding of this process is still limited. We set out to study a possible role for dynein in synapse integrity. Cytoplasmic dynein is a multisubunit intrace...

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Bibliographic Details
Published in:Mol Cell Proteomics
Main Authors: Gershoni-Emek, Noga, Mazza, Arnon, Chein, Michael, Gradus-Pery, Tal, Xiang, Xin, Li, Ka Wan, Sharan, Roded, Perlson, Eran
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2016
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Special Issue Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739670/
https://ncbi.nlm.nih.gov/pubmed/26598648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.049965
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