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Proteomic Analysis of Dynein-Interacting Proteins in Amyotrophic Lateral Sclerosis Synaptosomes Reveals Alterations in the RNA-Binding Protein Staufen1

Synapse disruption takes place in many neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). However, the mechanistic understanding of this process is still limited. We set out to study a possible role for dynein in synapse integrity. Cytoplasmic dynein is a multisubunit intrace...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Gershoni-Emek, Noga, Mazza, Arnon, Chein, Michael, Gradus-Pery, Tal, Xiang, Xin, Li, Ka Wan, Sharan, Roded, Perlson, Eran
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739670/
https://ncbi.nlm.nih.gov/pubmed/26598648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.049965
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