Proteomic Analysis of Dynein-Interacting Proteins in Amyotrophic Lateral Sclerosis Synaptosomes Reveals Alterations in the RNA-Binding Protein Staufen1

Synapse disruption takes place in many neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). However, the mechanistic understanding of this process is still limited. We set out to study a possible role for dynein in synapse integrity. Cytoplasmic dynein is a multisubunit intrace...

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Vydáno v:Mol Cell Proteomics
Hlavní autoři: Gershoni-Emek, Noga, Mazza, Arnon, Chein, Michael, Gradus-Pery, Tal, Xiang, Xin, Li, Ka Wan, Sharan, Roded, Perlson, Eran
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2016
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Special Issue Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739670/
https://ncbi.nlm.nih.gov/pubmed/26598648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.049965
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