Localization of RNAi Machinery to Axonal Branch Points and Growth Cones Is Facilitated by Mitochondria and Is Disrupted in ALS

Local protein synthesis in neuronal axons plays an important role in essential spatiotemporal signaling processes; however, the molecular basis for the post-transcriptional regulation controlling this process in axons is still not fully understood. Here we studied the axonal mechanisms underlying th...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Gershoni-Emek, Noga, Altman, Topaz, Ionescu, Ariel, Costa, Christopher J., Gradus-Pery, Tal, Willis, Dianna E., Perlson, Eran
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Molecular Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134038/
https://ncbi.nlm.nih.gov/pubmed/30233312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00311
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