Azurin interaction with the lipid raft components ganglioside GM-1 and caveolin-1 increases membrane fluidity and sensitivity to anti-cancer drugs

Membrane lipid rafts are highly ordered microdomains and essential components of plasma membranes. In this work, we demonstrate that azurin uptake by cancer cells is, in part, mediated by caveolin-1 and GM-1, lipid rafts’ markers. This recognition is mediated by a surface exposed hydrophobic core di...

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Detaylı Bibliyografya
Yayımlandı:Cell Cycle
Asıl Yazarlar: Bernardes, Nuno, Garizo, Ana Rita, Pinto, Sandra N., Caniço, Bernardo, Perdigão, Catarina, Fernandes, Fábio, Fialho, Arsenio M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2018
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6133334/
https://ncbi.nlm.nih.gov/pubmed/29963969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2018.1489178
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