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Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insulin resistance

Membrane microdomains (lipid rafts) are now recognized as critical for proper compartmentalization of insulin signaling. We previously demonstrated that, in adipocytes in a state of TNFα-induced insulin resistance, the inhibition of insulin metabolic signaling and the elimination of insulin receptor...

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Detalhes bibliográficos
Main Authors: Kabayama, Kazuya, Sato, Takashige, Saito, Kumiko, Loberto, Nicoletta, Prinetti, Alessandro, Sonnino, Sandro, Kinjo, Masataka, Igarashi, Yasuyuki, Inokuchi, Jin-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949342/
https://ncbi.nlm.nih.gov/pubmed/17699617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703650104
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