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Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insulin resistance

Membrane microdomains (lipid rafts) are now recognized as critical for proper compartmentalization of insulin signaling. We previously demonstrated that, in adipocytes in a state of TNFα-induced insulin resistance, the inhibition of insulin metabolic signaling and the elimination of insulin receptor...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kabayama, Kazuya, Sato, Takashige, Saito, Kumiko, Loberto, Nicoletta, Prinetti, Alessandro, Sonnino, Sandro, Kinjo, Masataka, Igarashi, Yasuyuki, Inokuchi, Jin-ichi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949342/
https://ncbi.nlm.nih.gov/pubmed/17699617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703650104
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